Creamy Pesto Penne Chicken

Featured in: Family Comfort Plates

This Italian-inspired dish features tender chicken pieces and perfectly cooked penne pasta enveloped in a luscious creamy pesto sauce. The blend of rich cream, fresh basil pesto, and Parmesan creates a smooth and flavorful coating, complemented by sautéed onion and garlic for depth. Quick and straightforward to prepare, it’s ideal for busy weeknights or casual meals, garnished with fresh basil leaves and extra Parmesan to enhance the experience. Adjust the creaminess by adding reserved pasta water for desired consistency.

Updated on Sat, 15 Nov 2025 09:09:00 GMT
Golden chicken pieces and creamy pesto penne are coated in a vibrant, flavorful sauce. Pin it
Golden chicken pieces and creamy pesto penne are coated in a vibrant, flavorful sauce. | weeknightwhisk.com

A comforting Italian-inspired pasta dish featuring tender chicken, al dente penne, and a luscious creamy pesto sauce. Perfect for weeknight dinners or casual gatherings.

The first time I made this creamy pesto penne and chicken was for a spontaneous midweek dinner with friends. Everyone cleaned their plates and kept commenting how much they loved the sauce.

Ingredients

  • Boneless skinless chicken breasts: About 400 g, cut into bite-sized pieces
  • Penne pasta: 350 g
  • Heavy cream: 200 ml
  • Grated Parmesan cheese: 40 g
  • Basil pesto: 80 g, store-bought or homemade
  • Onion: 1 small, finely chopped
  • Garlic: 2 cloves, minced
  • Olive oil: 2 tbsp
  • Salt and freshly ground black pepper: To taste
  • Fresh basil leaves: Optional, for garnish
  • Extra grated Parmesan: Optional, for garnish

Instructions

Cook the pasta:
Boil penne in a large pot of salted water until al dente. Drain, reserving 100 ml pasta water.
Cook chicken:
Heat olive oil in a large skillet over medium high heat. Add chicken, season with salt and pepper, and sauté for 5 minutes until golden and cooked. Remove and set aside.
Cook vegetables:
In the same skillet, add chopped onion and cook for 2–3 minutes until softened. Add garlic and sauté for 30 seconds until fragrant.
Make the sauce:
Reduce heat to medium. Pour in cream. Bring to simmer. Stir in pesto and Parmesan until smooth.
Combine chicken:
Return cooked chicken to skillet and toss in the sauce.
Add pasta:
Add drained penne, tossing to combine. Add reserved pasta water to adjust sauce consistency.
Season and serve:
Season with salt and pepper. Serve with fresh basil and extra Parmesan if desired.
Al dente penne pasta dish, tossed with chicken in a rich, creamy pesto sauce, ready to serve. Pin it
Al dente penne pasta dish, tossed with chicken in a rich, creamy pesto sauce, ready to serve. | weeknightwhisk.com

This is the recipe my family requests every time we want something cozy and comforting but a little bit fancy. We usually share stories around the table while enjoying every bite.

Serving Suggestions

Pair with a crisp green salad, crusty bread, or a glass of chilled Pinot Grigio. Garnish with extra basil for a pop of freshness.

Allergen & Nutrition Info

This recipe contains dairy, wheat, and may contain nuts if your pesto includes pine nuts. Each serving has about 620 calories, 27 g fat, 58 g carbs, and 36 g protein.

Variations

Swap half-and-half or whole milk for heavy cream for a lighter version. Use gluten free pasta for dietary needs. Try sun dried tomato pesto for a fun twist.

A close-up shot of hot Creamy Pesto Penne & Chicken, garnished with fresh basil and Parmesan. Pin it
A close-up shot of hot Creamy Pesto Penne & Chicken, garnished with fresh basil and Parmesan. | weeknightwhisk.com

This creamy chicken pesto penne is irresistible every time. Enjoy it fresh and savor every comforting bite!

Common Questions

How can I achieve a creamy pesto sauce consistency?

Simmer the cream gently while stirring in pesto and Parmesan until smooth. Use reserved pasta water incrementally to thin the sauce to your preference.

What pasta is best for creamy pesto dishes?

Penne pasta is ideal due to its tube shape which holds the sauce well, ensuring each bite is flavorful.

Can I use homemade pesto for this dish?

Absolutely, homemade basil pesto enhances freshness, but quality store-bought pesto also works well.

How do I keep chicken tender and juicy?

Sauté bite-sized chicken pieces over medium-high heat just until golden and cooked through to retain moisture and tenderness.

What garnishes complement creamy pesto penne and chicken?

Fresh basil leaves and extra grated Parmesan add aroma and depth, elevating the dish’s flavor and presentation.

Is it possible to lighten the sauce without losing flavor?

Yes, substitute half-and-half or whole milk for heavy cream, keeping in mind the sauce will be thinner but still tasty.

Creamy Pesto Penne Chicken

Tender chicken and penne pasta coated in a smooth, flavorful creamy pesto sauce for easy meals.

Prep Time
15 min
Cook Time
25 min
Time Needed
40 min
Created by Ella Thompson


Skill Level Easy

Cuisine Italian

Makes 4 Portions

Dietary Info None specified

What You'll Need

Poultry

01 2 boneless, skinless chicken breasts (about 14 oz), cut into bite-sized pieces

Pasta

01 12 oz penne pasta

Dairy

01 ⅞ cup heavy cream
02 ¼ cup grated Parmesan cheese

Pesto

01 ⅓ cup basil pesto (store-bought or homemade)

Vegetables

01 1 small onion, finely chopped
02 2 cloves garlic, minced

Pantry

01 2 tbsp olive oil
02 Salt and freshly ground black pepper, to taste

Garnish (optional)

01 Fresh basil leaves
02 Extra grated Parmesan cheese

Step-by-Step

Step 01

Cook Pasta: Boil penne in a large pot of salted water until al dente as per package directions. Drain, reserving ⅓ cup of pasta water.

Step 02

Sauté Chicken: Heat olive oil in a large skillet over medium-high heat. Season chicken with salt and pepper, then cook for 5–6 minutes until golden and cooked through. Remove and set aside.

Step 03

Cook Aromatics: In the same skillet, sauté chopped onion for 2–3 minutes until softened. Add minced garlic and cook for 30 seconds until fragrant.

Step 04

Prepare Sauce: Lower heat to medium. Stir in heavy cream, bring to a gentle simmer, then whisk in basil pesto and Parmesan cheese until smooth.

Step 05

Combine Chicken with Sauce: Return chicken to skillet, stirring to coat evenly with sauce.

Step 06

Add Pasta to Sauce: Toss drained penne into skillet with chicken and sauce; add reserved pasta water gradually to reach desired consistency.

Step 07

Season and Serve: Adjust seasoning with salt and pepper as needed. Serve immediately, garnished with fresh basil leaves and extra Parmesan if desired.

Tools Required

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Colander

Allergy Notice

Go through every ingredient to identify allergens and talk to your healthcare provider if you have concerns.
  • Contains dairy (heavy cream, Parmesan), wheat (pasta), and nuts (if pesto contains pine nuts).
  • Check pesto ingredients for potential allergens.

Nutrition Information (per portion)

Nutrition details are for general reference and shouldn't replace advice from your doctor.
  • Caloric Content: 620
  • Fats: 27 g
  • Carbohydrates: 58 g
  • Proteins: 36 g